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WASHINGTON (AP) - Scientists mapping genetics of two of the nation's leading cancers have found almost 200 mutated genes in breast and colorectal tumors, many of them never before suspected of helping cancer form and spread.
Doctors have long known it takes a cascade of genetic flaws to trigger any of the myriad types of cancer. Which genes are working improperly also determines if a malignancy is especially aggressive, and even whether a particular treatment is likely to work.
Finding those genes-run-amok could lead to better cancer treatments and even ways to prevent tumors. But scientists have found only a fraction of them.
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